411 Developmental Regulation of Sam Pointed Domain Ets Factor (SPDEF) in Rat Ileum Cultured With Bile Acids

Autor:	Melissa D. Halpern, Daniel T. Rogan, Teresa E. Estrada, Sarah Mount Patrick, Harrison A. Frisk
Rok vydání:	2012
Předmět:	medicine.medical_specialty Hepatology Period (gene) Gastroenterology Endogeny Ileum Biology digestive system Small intestine Jejunum Endocrinology medicine.anatomical_structure Internal medicine medicine Duodenum Total Tissue
Zdroj:	Gastroenterology. 142:S-91
ISSN:	0016-5085
DOI:	10.1016/s0016-5085(12)60347-3
Popis:	fibers as a percentage of total tissue area (μm2). The nerve volume densities were significantly decreased in the jejunum (23.7 vs. 31.3; p 0.05) and duodenum (30.1 vs. 28.8; p > 0.05). These findings suggest that endogenous microbiota are necessary for the normal patterning of the ENS in the early postnatal period, particularly in the mid to distal small intestine and colon. Further studies are needed to determine whether the mechanisms by which the endogenous microbiota act on the ENS involve a direct effect on neural cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::423da8e6167ada1f4ce07ae94961bae5 https://doi.org/10.1016/s0016-5085(12)60347-3 Zobrazit plný text záznamu