Acute Effects of an Artificial Surfactant (Exosurf) Administered as an Aerosol in Sheep with Oleic Acid-Induced Lung Injury

Autor: J. F. Murray, B. J. Escudier, J. M. Hoeffel, M. Zelter
Rok vydání: 1988
Předmět:
Zdroj: Surfactant Replacement Therapy ISBN: 9783642733079
DOI: 10.1007/978-3-642-73305-5_30
Popis: Several investigators have found evidence of surfactant abnormalities in patients with ARDS (Asbaugh et al. 1967; Hallman et al. 1982; Petty et al. 1977). This raises the possibility that lowering intra-alveolar surface tension by surfactant administration might improve the gas exchange disturbances, abnormal mechanics and increased permeability that characterize acute lung injury.
Databáze: OpenAIRE