Vitamin D levels in a sample of Egyptian patients with multiple sclerosis
| Autor: | Doaa M Abdelaziz, Doaa A Elaidy, Mohamed M. Fouad, Dina A. Zamzam, Azza A Abd-Elaziz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Expanded Disability Status Scale business.industry General Neuroscience Multiple sclerosis medicine.disease Assay technique Gastroenterology vitamin D deficiency 03 medical and health sciences Psychiatry and Mental health 030104 developmental biology 0302 clinical medicine Endocrinology Internal medicine medicine Etiology Vitamin D and neurology Surgery Neurology (clinical) Pshychiatric Mental Health business 030217 neurology & neurosurgery |
| Zdroj: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery. 53:107 |
| ISSN: | 1110-1083 |
| Popis: | Background Environmental factors such as vitamin D deficiency have been linked to the etiology of multiple sclerosis (MS) through interaction with genetic factors. Researches must be carried out to answer the question whether the relationship between vitamin D and MS is consistent and reproducible. Objective The aim of the present study was to assess the level of vitamin D in Egyptian MS patients. Subjects and methods In total, 111 patients with MS and 33 normal subjects were included in this study. Vitamin D level was estimated for each participant using the enzyme linked immunosorbent assay technique. Results Vitamin D levels were significantly lower among MS patients (ranging from 5 to 75 ng/ml with a mean ± SD of 26.4 ± 18.5) when compared with controls [ranging from 25 to 80 ng/ml with a mean of 51.2 ± 19.6 (P < 0.001)]. High expanded disability status scale scores were found to be related to low vitamin D levels. Conclusion Patients with MS tended to have lower vitamin D levels, and those with higher (expanded disability status scale) scores were more likely to have lower levels of vitamin D. |
| Databáze: | OpenAIRE |
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