| Popis: |
Archer Martin and Richard Synge realized that they had done much more than simply invent a new method of chemicals separation. Not only could partition chromatography separate the different amino acid components of wool proteins, but also it might be used to determine their precise linear order—or, as Martin and Synge called it, their sequence. To test this idea, they embarked on a ‘boastful undertaking’ with their colleagues Hugh Gordon and Raphael Consden to use partition chromatography to determine the order of amino acids in the antibiotic gramicidin S. To help with the study of gramicidin S, Synge also recruited Fred Sanger and Dorothy Hodgkin, two young scientists who would both go on to distinguish themselves through their respective work on insulin. |
