Secretory Meningiomas
| Autor: | Jakob Matschke, Pedram Emami, Sven O. Eicker, Manfred Westphal, Malte Mohme, Jan Regelsberger |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Brain tumor General Medicine Perioperative medicine.disease Pathophysiology Meningioma 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Edema Eosinophilic Medicine Surgery Neurology (clinical) medicine.symptom business Peritumoral Brain Edema 030217 neurology & neurosurgery Secretory Meningioma |
| Zdroj: | Neurosurgery Clinics of North America. 27:181-187 |
| ISSN: | 1042-3680 |
| Popis: | Secretory meningiomas (SM) represent a rare variant of the most common benign intracranial brain tumor. Defined by the histologic appearance of eosinophilic glandular formations and periodic-acidic Schiff-positive pseudopsammoma bodies, SM are characterized by unique molecular alterations, a disproportional occurrence of reactive peritumoral brain edema, and a clinical course that demands for increased awareness for perioperative complications. The frequent presence of extensive peritumoral edema has become a hallmark of SM and can be associated with life-threatening complications. The exact pathophysiology of edema formation in SM is still unknown. |
| Databáze: | OpenAIRE |
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