APPLICATION OF NANOANTIBIOTICS APPROACH AGAINST ANTI-BACTERIAL RESISTANCE

Autor: AYA YASEEN MAHMOOD ALABDALI, MARWAH SAMI KZAR, SASIKALA CHINNAPPAN, RAVISHANKAR RAM MANI, MALARVILI SELVARAJA, KOK JING WEN, LAI SALLY, FU WAI KUANG
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Applied Pharmaceutics. :34-39
ISSN: 0975-7058
Popis: Despite the fact that we live in an era with unique and advanced technology for revealing underlying molecularly creating new drugs and disease mechanisms, infectious illnesses remain one of the world's major health issues. Antimicrobial agents now available against pathogenic microorganisms are insufficient to combat the problems posed by novel multidrug-resistant (MDR) infections. Antimicrobial drug restrictions are producing negative side effects and the development of multiple drug resistance. Drug resistance will necessitate the use of high-dose antibiotics, resulting in severe toxicity and the development of new medicines. Nanoantibiotics, a new type of antimicrobial agent that combines antimicrobial compounds with nanoparticles, has been created to solve these shortcomings. Additionally, previous reports stated that the pharmacokinetics profiles and have quicker ingestion in circulatory framework. In this subject, we will clarify the various sorts of nanoantibiotics, their instrument of activity, key targets and medication discharge components. We will likewise portray some significant microbial elements that will influence the activity of nanoantibiotics.
Databáze: OpenAIRE