The antimicrobial efficacy of ‘MGP’ gutta-percha in vitro

Autor: A. L. Shur, J. C. Fenno, Christine M. Sedgley
Rok vydání: 2003
Předmět:
Zdroj: International Endodontic Journal. 36:616-621
ISSN: 0143-2885
DOI: 10.1046/j.1365-2591.2003.00699.x
Popis: Aim To determine whether ‘MGP’ gutta-percha (Westport, CT, USA), a commercially available gutta-percha containing iodoform, inhibits the growth of potential endodontic pathogens. Methodology Inocula of Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus sanguis, Fusobacterium nucleatum and Actinomyces odontolyticus were spread onto the surface of agar plates. ‘MGP’ gutta-percha cones presoaked in sterile water were transferred to the inoculated agar and incubated at 37 °C aerobically or anaerobically as required for optimal growth. Identical studies were performed using iodoform-free gutta-percha and sterile paper disks saturated with 10% povidone–iodine. Following incubation, zones of inhibition around the ‘MGP’ gutta-percha, iodoform-free gutta-percha and disks were evaluated. Results Povidone–iodine inhibited all the strains. Iodoform-free gutta-percha inhibited S. sanguis and A. odontolyticus. ‘MGP’ gutta-percha inhibited S. aureus, S. sanguis, A. odontolyticus and F. nucleatum. Neither iodoform-free gutta-percha nor ‘MGP’ gutta-percha inhibited growth of E. faecalis, E. coli or P. aeruginosa. Conclusions Compared to iodoform-free gutta-percha, iodoform-containing ‘MGP’ gutta-percha had an inhibitory effect in vitro on S. aureus and F. nucleatum, but not on E. faecalis, E. coli or P. aeruginosa.
Databáze: OpenAIRE