Immunity in Patients Treated with Cis-Platinum

Autor: Contessi E, C. Toso, Bramezza M, Cartei G, Comelli M
Rok vydání: 1988
Předmět:
Zdroj: Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy ISBN: 9781461289678
DOI: 10.1007/978-1-4613-1717-3_51
Popis: Cis-platinum (DDP) is one of the most active compounds available in the treatment of cancer. Effects of DDP on the immune system have recently been explored (1, 2, 3). Initial evidence appeared to classify DDP among immunosuppressive agents: graft-versus-host responses were suppressed in animals treated with this drug (4); moreover the growth of B and T cells in colture (5) was inhibited by DDP, as well as monocyte chemotaxis (6).
Databáze: OpenAIRE