Bolus doses of esmolol for the prevention of postintubation hypertension and tachycardia

Autor:	Deena Kapala, Joseph S. Mallon, Ernest Hew, Robert W. Wald
Rok vydání:	1990
Předmět:	ST depression Tachycardia business.industry medicine.medical_treatment Hemodynamics Placebo Esmolol Anesthesiology and Pain Medicine Bolus (medicine) Anesthesia Heart rate medicine Intubation medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug
Zdroj:	Journal of Cardiothoracic Anesthesia. 4:27-30
ISSN:	0888-6296
DOI:	10.1016/s0888-6296(11)80007-4
Popis:	This study was designed to determine the safety and efficacy of 100-mg and 200-mg bolus doses of esmolol in the prevention of intubation-associated hypertension, tachycardia, ST depression, and dysrhythmias. Forty-five patients undergoing noncardiac surgery were randomly allocated to receive either placebo, esmolol, 100 mg, or esmolol, 200 mg, intravenously, 90 seconds prior to intubation. Both doses of esmolol decreased the mean maximum increase in heart rate and rate-pressure product by approximately 36% [ P P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::41e0a4d543fa44b945911570bdeedc67 https://doi.org/10.1016/s0888-6296(11)80007-4 Zobrazit plný text záznamu