An alternate method for the synthesis of 2-aryl/alkyl-5-bromo-7-methoxy benzofurans; application to the synthesis of Egonol, Homoegonol, and analogs via Heck reaction
| Autor: | R.S. Mali, Kishor R. More |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Vanillin Aryl Organic Chemistry Homoegonol 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound chemistry Heck reaction Drug Discovery Organic chemistry Methyl acrylate Palladium catalyst Alkyl |
| Zdroj: | Tetrahedron. 72:7496-7504 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2016.09.068 |
| Popis: | We herein report the general, versatile, and convenient method for the synthesis of 2-arly/alkyl-5-bromo-7-methoxy benzofurans from easily available o -Vanillin in five steps. These benzofurans was successfully converted into biological active natural products Egonol, Homoegonol, and analogous on applying Heck reaction using ethyl/methyl acrylate in the presence of palladium catalyst. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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