A Study on a New Index of Vascular Stiffness: Gender Difference and Risk Factors

Autor: Fuyou Liang, Xianghong Luo, Xiuqin Wu, Zhaojun Li, Jianxiong Chen, Yongqiang Hong, Yuchen Xie
Rok vydání: 2021
Předmět:
DOI: 10.21203/rs.3.rs-812184/v1
Popis: Background: Previous studies have found that the gender differences have important influences on cardiovascular events, and arterial stiffness is an independent risk factor for cardiovascular events. The arterial pressure volume index (API) is a new indicator for the noninvasive assessment of muscular arterial stiffness. This study was aimed to preliminarily investigate on the gender differences and influencing factors of API from Chinese people, and to discuss the practical application implications of it.Methods: A total of 11118 outpatients were randomly selected and divided into 5 groups according to the age from low to high quintile (Q1: < 37 years old group, Q2: ≥ 37 years old group, Q3: ≥ 51 years old group, Q4: ≥ 61 years old group and Q5: ≥ 69 years old group). The API was obtained by using the cuff oscillation wave for every subject. API≥31 was defined as high API, and body mass index (BMI)≥24 kg/m2 was diagnosed as overweight. The differences of API and high API incidence between male and female subjects in the five groups were compared by Pearson correlation analysis. The risk factors of high API incidence were analyzed by multivariate logistic regression. Results: ①The differences in API and systolic blood pressure(SBP) between the 5 groups were statistically significant, and they increased with age (all PPPPPPConclusion: Among Chinese people of different ages, API differed between male and female; in the whole subjects, the risk of high API is higher for female subjects and overweight subjects.
Databáze: OpenAIRE