Fabrication of a poly(ɛ-caprolactone)/starch nanocomposite scaffold with a solvent-casting/salt-leaching technique for bone tissue engineering applications
| Autor: | Fathollah Moztarzadeh, Safa Taherkhani |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Materials science
Nanocomposite Polymers and Plastics Starch Composite number technology industry and agriculture 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Microstructure 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films Polyester Contact angle chemistry.chemical_compound Compressive strength chemistry Materials Chemistry Composite material 0210 nano-technology Porosity |
| Zdroj: | Journal of Applied Polymer Science. 133 |
| ISSN: | 0021-8995 |
| DOI: | 10.1002/app.43523 |
| Popis: | A series of nanocomposite scaffolds of poly(ɛ-caprolactone) (PCL) and starch with a range of porosity from 50 to 90% were fabricated with a solvent-casting/salt-leaching technique, and their physical and mechanical properties were investigated. X-ray diffraction patterns and Fourier transform infrared spectra confirmed the presence of the characteristic peaks of PCL in the fabricated scaffolds. Microstructure studies of the scaffolds revealed a uniform pore morphology and structure in all of the samples. The experimental measurements showed that the average contact angle of the PCL/starch composite was 88.05 ± 1.77°. All of the samples exhibited compressive stress/strain curves similar to those of polymeric foams. The samples with 50, 60, 70, and 80 wt % salt showed compressive-load-resisting capabilities in the range of human cancellous bone. With increasing porosity, a significant decrease in the mechanical properties of the scaffolds was observed. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43523. |
| Databáze: | OpenAIRE |
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