Mesenchymal Stromal/Stem Cells in the Tumor Microenvironment and Their Role in Tumor Progression

Autor:	Venus Shahabi Raberi, Samira Abdollahi Moghadam, Ensieh Sharafi, Maryam Poudineh, Behnaz Barghgir, Maryam Molaee Eshgh Abad, Morteza Jafarinia, Hossein Kargar Jahromi
Rok vydání:	2022
Předmět:	General Medicine
Zdroj:	Galen Medical Journal. 11:e2637
ISSN:	2322-2379 2588-2767
Popis:	Mesenchymal stromal/stem cells (MSCs) are a source of stem cells that can be easily harvested and differentiated into numerous cells. Over the past few decades, these cells have been introduced as promising therapeutic candidates for different diseases. Different studies have shown the role of these cells in regenerative medicine. Tumor growth is correlated with the interactions between MSCs and tumor cells in the tumor microenvironment. The precise key role played by MSCs in the progression of tumors is under question, and the effect of MSCs on the tumor is controversial it might involve the development of tumor initiation or prevent the spread of already existing ones. In this study, we reviewed the role of MSCs in the tumor microenvironment and their influence on promoting or inhibiting tumor progression.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::41b9fecd7fdc9356c548bdddbd5cd4ad https://doi.org/10.31661/gmj.v11i.2637 Zobrazit plný text záznamu