Protocol for the Reducing Fear-Avoidance of Memory Loss (REFRAME) Study: A randomized feasibility trial investigating the impact of a low-intensity psychological intervention on fear-of-memory loss and quality of life in older adults

Autor: O’Loughlin, Patricia, Pavithra, Pavithra, Regan, John, Bennett, Marc, Knight, Rachel, Lenaert, Bert, Taddeo, Michelle, Marquez, Melissa, Griffith, James, Farina, Francesca
Rok vydání: 2022
Předmět:
DOI: 10.17605/osf.io/whqkg
Popis: Dementia is the most feared disease associated with aging. If left unchecked, these fears can have harmful consequences even in the absence of cognitive decline. Fear of dementia is associated with poorer health outcomes, reduced psychological wellbeing, increased memory failures and lower quality of life in older adults. We will therefore conduct a randomised control feasibility study to determine the impact of a tailored, web-based mindfulness programme to reduce anxiety and increase quality of life in older adults experiencing dementia-related fear. One group will be given psycho-education and brief mindfulness training to manage psychological distress. A second group will be given psycho-education, brief mindfulness training and additional modules targeting maladaptive behavioural avoidance (e.g. social and cognitive withdrawal). Our recent etiological model posits that maladaptive behavioural avoidance strategies critically underlie psycho-social dysfunction associated with the fear of memory loss. Thus, we predict better clinical outcomes in the second group; these include fear of memory loss (primary outcome) and older adult quality of life as well as subjective memory failures (secondary outcomes). Outcome measures will be applied at five time points (pre-, baseline, interim-, and post-intervention as well as at 3-month follow up). Data will be analysed using standard ANOVAs and regression models. Qualitative interviews will be conducted with participants upon completion of the intervention and data will be analysed using NVivo software. This study was approved by the IRB at Nortwestern University (USA) and data collection will take place between April and August 2021.
Databáze: OpenAIRE