Effects of Bifidobacterium animalis subsp. lactis HN019 on ligature-induced periodontitis in rats with experimental rheumatoid arthritis
| Autor: | Daniela Bazan Palioto, C. Leite-Panissi, Michel Reis Messora, Sérgio Luiz de Souza Salvador, Luiz Felipe Ramalho de Oliveira, Flávia A.C. Furlaneto, Arthur B. Novaes, Renata Silva Cardoso, Renato Corrêa Viana Casarin, Pedro Henrique Felix Silva |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Necrosis Connective tissue Microbiology Gastroenterology Bone resorption 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Periodontitis biology business.industry Interleukin medicine.disease biology.organism_classification Bifidobacterium animalis 030104 developmental biology medicine.anatomical_structure Rheumatoid arthritis 030211 gastroenterology & hepatology Anaerobic bacteria medicine.symptom business |
| Zdroj: | Beneficial Microbes. 11:33-46 |
| ISSN: | 1876-2891 1876-2883 |
| DOI: | 10.3920/bm2019.0038 |
| Popis: | The purpose of this study was to evaluate the effects of systemic administration of the probiotic Bifidobacterium animalis subsp. lactis HN019 (HN019) on ligature-induced periodontitis in rats with experimental rheumatoid arthritis (RA). 28 rats were divided into four groups (n=7): RA (rheumatoid arthritis), RA/PROB (probiotic), RA/EP (experimental periodontitis) and RA/EP/PROB. From day zero, HN019 was added daily to the water of the PROB groups animals until the end of the experiment. From day seven, RA was induced. On day 28, in EP groups, ligatures were positioned around mandibular first molars and remained in position for 11 days, in order to induce periodontitis. The animals were euthanised on day 39. Microtomographic, histomorphometric, immunoenzymatic and microbiological analyses were performed. Data were statistically analysed (P |
| Databáze: | OpenAIRE |
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