Correlation of Diffusion-weighted MR imaging and FDG PET / CT in the Diagnosis of Metastatic Lymph Nodes of Head and Neck Malignant Tumors

Autor: Şamil Şahin, Yaşar Kemal Duymaz, Burak Erkmen, Burak Karabulut, İldem Deveci, Mehmet Sürmeli, Aslı Şahin Yılmaz, Çağatay Oysu
Rok vydání: 2023
Zdroj: European Journal of Therapeutics.
ISSN: 2564-7040
2564-7784
DOI: 10.58600/eurjther.20232902-450.y
Popis: Objectives: The aim of this study was to investigate the efficacy of DW-MRI as a reliable imaging modality for detecting metastatic neck lymph nodes of head and neck SCC. Methods: 32 patients underwent FDG PET/CT and diffusion-weighted MRI were evaluated. Histopathologic analysis of lymph node metastases was used as the gold standard for assessment. We analyzed differences in sensitivity, specificity, accuracy, positive predictive value and negative predictive value among the imaging modalities using the Chi-square test. Their discriminative power evaluated using the Receiver-Operating Characteristic curve and calculation of the area under the curve. The correlation between ADCmin and SUVmax was calculated using the Spearman test. SPSS 24 was used for statistical analyses. P value of 0.05 indicates a statistically significant difference. Results: A total of 32 patients with 50 neck dissections with head and neck SCC included. Sensitivity, specificity, accuracy, positive and negative predictive value of neck palpation was %72, %60, %70, %62 and %80 respectively. Sensitivity, specificity, accuracy, positive and negative predictive value of DW-MRI was %87,5, %96,2, %92, %95,5 and %89,3 respectively, according to ADCmin cutoff value 0.82×10-3s/mm2 . Sensitivity, specificity, accuracy, positive and negative predictive value of FDG-PET/CT was %91,7, %100, %96, %100 and %92,9 , respectively ,according to SUVmax cutoff value 3.4. For all neck dissections, there was a statistically significant inverse correlation between ADCmin and SUVmax (P
Databáze: OpenAIRE
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