Investigations on sterols XXXVII: New routes to 9,10-isomers of 6-dehydroprogesterone

Autor:	M. P. Rappoldt, T.H.R. Rix
Rok vydání:	1971
Předmět:	Hydrolysis Chemistry Organic chemistry General Chemistry Vitamin D Analogue Pyrolysis Isomerization Ethylenedioxy
Zdroj:	Recueil des Travaux Chimiques des Pays-Bas. 90:27-32
ISSN:	0165-0513
DOI:	10.1002/recl.19710900105
Popis:	The synthesis of 6-dehydro-9β, 10α-progesterone (IV) from progesterone via irradiation of 3,20-bis(ethylenedioxy)pregna-5,7-diene (II) is described. An analogous synthesis has been accomplished via 3-(ethylenedioxy)pregna-5,7-dien-20-one (VI). Pyrolysis of the 9,10-seco-bisacetal (IX), a vitamin D analogue, followed by hydrolysis and isomerization, gave the 8α,10α-isomer of 6-dehydroprogesterone (XI).
Databáze:	OpenAIRE
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