Beneficial Effects of Telmisartan in an HIV+ Diabetic Insulin-Dependent Patient
| Autor: | Claudio Ucciferri, Katia Falasca, Paola Mancino, Jacopo Vecchiet |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pharmacology
Drug medicine.medical_specialty education.field_of_study business.industry Insulin medicine.medical_treatment media_common.quotation_subject Immunology Population medicine.disease Metformin Blood pressure Internal medicine Diabetes mellitus medicine Immunology and Allergy Metabolic syndrome Telmisartan education business media_common medicine.drug |
| Zdroj: | International Journal of Immunopathology and Pharmacology. 22:853-857 |
| ISSN: | 2058-7384 |
| Popis: | In HIV-infected patients with metabolic disorders, as in the general population, there is evidence of hypertension requiring pharmacological treatment. The presence of diabetes constitutes a cluster of particularly high cardiovascular risks in patients, both regarding diabetic damage and hypertensive damage. We used telmisartan to manage high blood pressure values in an HIV-positive patient with insulin-dependent diabetes. Surprisingly, insulin therapy had to be suspended because of hypoglycemic fits and treatment with metformin was started. In conclusion, telmisartan was effective and well-tolerated for the control of hypertension in this case and improved sensitivity to insulin. There are interesting effects of this drug in HIV-positive diabetic patients. Thus, if further studies confirm these effects, telmisartan may be the anti-hypertensive drug of first choice in HIV-infected subjects on combined antiretroviral therapy affected with diabetes and metabolic disorders. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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