Industry Perspectives on Process Analytical Technology: Tools and Applications in API Manufacturing

Autor:	Arani Chanda, Shailendra Bordawekar, Samrat Mukherjee, John P. Higgins, Howard W. Ward, Mark A. LaPack, Adrian M. Daly, Bing-Shiou Yang, John D. Orr, James E. Morgado, Todd D. Maloney, George L. Reid, Aaron W. Garrett
Rok vydání:	2015
Předmět:	Active ingredient Engineering business.industry Process analytical technology Organic Chemistry Physical and Theoretical Chemistry business Process engineering
Zdroj:	Organic Process Research & Development. 19:1174-1185
ISSN:	1520-586X 1083-6160
DOI:	10.1021/acs.oprd.5b00088
Popis:	The IQ Consortium reports on the current state of process analytical technology (PAT) for active pharmaceutical ingredient (API) manufacturing in branded pharmaceutical companies. The article describes the application of PAT in manufacturing and provides representative examples in four common pharmaceutical unit operations: reaction and workup, crystallization, drying, and milling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4153173c4b49f2d2192f0eefe07707b8 https://doi.org/10.1021/acs.oprd.5b00088 Zobrazit plný text záznamu