Evaluation of cardiovascular sympathetic reactivity in Normotensive offspring of Hypertensive parents

Autor: P R Devaki
Rok vydání: 2013
Předmět:
Zdroj: IOSR Journal of Dental and Medical Sciences. 4:1-3
ISSN: 2279-0853
2279-0861
Popis: Background: Sympathetic reactivity is defined as an exaggerated response to stress. Studies have shown that enhanced sympathetic response to stress tilts the balance towards Sympathetic over activity which in turn indicates a pre hypertensive state. Genetic predisposition definitely plays an important role in the development of hypertension. Hence, there is a need to explore the Sympathetic reactivity in children of hypertensive parents. Aim & Objective: The aim of this study is to assess the cardiovascular response to sympathetic activity in Normotensive off spring of Hypertensive parents (NH) and compare the same with Normotensive off spring of Normotensive parents (NN). Materials and Methodology: 60 children of age group 18-22 years, both males and females with normal BMI were included in the study. Based on the questionnaire they were grouped as Normotensive children of Hypertensive parents (NH) and Normotensive children of Normotensive parents (NN). Heart rate and Blood pressure at rest and during isometric hand grip exercise and mental stress test was measured. Statistical analysis was done to compare the blood pressure and heart rate at rest and during isometric hand grip exercise and mental stress test between both the groups using nonparametric test. Results: A statistically significant increase in diastolic blood pressure was observed in offspring of hypertensive parents when compared to the offspring of normotensive parents indicating sympathetic overactivity . Keywords-Isometric hand grip, Mental stress test, Sympathetic reactivity.
Databáze: OpenAIRE