Environmentally Benign Synthesis of Fluorinated Pyrazolone Derivatives and Their Antimicrobial Activity

Autor:	Bhausaheb K. Karale, C. H. Gill, N. R. Dalvi, M. S. More, S. B. Kale, Sharad N. Shelke
Rok vydání:	2007
Předmět:	chemistry.chemical_compound Trifluoromethyl chemistry Sonication Proton NMR Organic chemistry Pyrazolone derivatives Fluorine containing General Medicine Methylene Antimicrobial Combinatorial chemistry
Zdroj:	ChemInform. 38
ISSN:	1522-2667 0931-7597
Popis:	Various fluorine containing 4-[-3-(4-aryl)-1-phenyl-1H-pyrazol-4-yl)methylene]-3-(trifluoromethyl)-1-phenyl-1H-pyrazol-5(4H)-one 3a-g and 3-(trifluoromethyl)-4-(4-oxo-4H-chromon-3-yl)methylene-1-phenyl-1H-pyrazol-5(4H)-one 5;i-k have been synthesized by conventional and non-conventional method. The synthesis 3 and 5 highlights a comparative study of conventional, ultrasonication and microwave techniques. All products have been characterized by IR, 1 H NMR, MS study aid screened for their antimicrobial activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::413c7b926a39f5519df123ff4b627532 https://doi.org/10.1002/chin.200746104 Zobrazit plný text záznamu Plný text