Associations between apolipoprotein B and selected perfluoroalkyl substances among diabetics and nondiabetics
| Autor: | Ram B. Jain, Alan M. Ducatman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Apolipoprotein B National Health and Nutrition Examination Survey Health Toxicology and Mutagenesis Population Disease 010501 environmental sciences 01 natural sciences Perfluorononanoic acid chemistry.chemical_compound Diabetes mellitus Internal medicine medicine Environmental Chemistry education 0105 earth and related environmental sciences chemistry.chemical_classification education.field_of_study biology business.industry Confounding Fatty acid General Medicine medicine.disease Pollution Endocrinology chemistry biology.protein lipids (amino acids peptides and proteins) business |
| Zdroj: | Environmental Science and Pollution Research. 28:13819-13828 |
| ISSN: | 1614-7499 0944-1344 |
| DOI: | 10.1007/s11356-020-11593-3 |
| Popis: | Previous population investigation of perfluoroalkyl substances (PFAS) features associations with lipids in a number of populations; these investigations have seldom included consideration of apolipoproteins. Apolipoprotein B (Apo B) fractions were considered in this descriptive analysis because they are essential to the assembly, transport, and cellular uptake of lipid classes associated with poorer health outcomes, and they are associated with incident and prevalent disease. Regression models stratified by diabetes and lipid lowering medication (LLM) status for data from National Health and Nutrition Examination Survey for 2007–2014 were fitted to interrogate associations between selected PFAS and Apo B for US adults aged ≥ 20 years. Adjusted concentrations of Apo B were positively associated with perfluorooctanoic acid (PFOA β = 0.03878, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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