Effect of extracellular matrix on cultured epidermocyte adhesion and proliferation

Autor: G. G. Serov, Pal'tsyn Aa, V. P. Tumanov, E. V. Glushchenko
Rok vydání: 1993
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 116:1432-1435
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00805169
Popis: The necessity of rapidly obtaining a large cellular mass in a lLrnited amount of time requires careful selection of the substrate for culturing. Various types of collagen [2-4,9-11] or fibronectin [1,6,7] are now most frequently used to improve cell adhesion to the culture flask surface. It is still unclear which substrate is best for epidermocyte growth, to what degree this or that substrate promotes adhesion, and, still more important, does a particular substrate influence subsequent proliferation of these cells? Here we compare the effects of various substrates: types I and III collagen and fibronectin on cultured epidermocyte adhesion and proliferation.
Databáze: OpenAIRE