A couple with gastrointestinal stromal tumor (GIST)

Autor:	Stephen Begbie, Pirooz Poursoltan
Rok vydání:	2009
Předmět:	Oncology medicine.medical_specialty GiST business.industry Incidence (epidemiology) Cancer Imatinib General Medicine Disease Malignancy medicine.disease digestive system diseases Pathogenesis Internal medicine medicine Stromal tumor business medicine.drug
Zdroj:	Asia-Pacific Journal of Clinical Oncology. 5:142-145
ISSN:	1743-7563 1743-7555
Popis:	We present a 70-year old woman with metastatic gastrointestinal stromal tumor (GIST) and her partner, a 79-year old man with multiple gastric GIST tumors. This tumor is considered a rare malignancy with a reported incidence of 6–13 new cases per million. Our patients were found to have different genetic mutations in the C-KIT gene as the cause of their disease but, given the rarity of this tumor, it raises a question about their possible exposure to carcinogens or another shared mechanism that might have been involved in the pathogenesis of this cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::411847e087d3ed86c5017afc3862e32d https://doi.org/10.1111/j.1743-7563.2009.01203.x Zobrazit plný text záznamu Plný text ve formátu PDF