Nuclear protein antigens in autoimmune Rheumatic and Connective Tissue Diseases1

Autor:	C.M. Wallis, S. Dahi, G. Naxakis, Alexander J. MacGILLIVRAY
Rok vydání:	1981
Předmět:	urogenital system RNA Connective tissue A protein Cell Biology Biology Molecular biology medicine.anatomical_structure Antigen RNP ANTIGEN Isotonic Immunology medicine Nuclear protein Small nuclear RNA
Zdroj:	Cell Biology International Reports. 5:69-72
ISSN:	0309-1651
DOI:	10.1016/0309-1651(81)90159-4
Popis:	Two nuclear antigens, Sm and RNP, that act as markers in Systemic Rheumatic (SRD) and Connective Tissue Diseases (CTD) have been studied with regard to their composition and biochemical properties. RNP antigen appears to be a 10S nuclear RNP particle containing SnRNA. Sm antigen, formerly considered to be a protein, may also contain RNA. Although both antigens are considered to be saline soluble, evidence suggests that they are part of a nuclear structure that is only slowly dissociated under isotonic conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::40f4c6c57a61a8c88633823952251bf4 https://doi.org/10.1016/0309-1651(81)90159-4 Zobrazit plný text záznamu