Carbamazepine-induced acute liver failure as part of the DRESS syndrome
| Autor: | Syn Wk, Munir Pirmohamed, Mutimer Dj, Dean J. Naisbitt, Holt Ap |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry General Medicine Carbamazepine Asymptomatic Gastroenterology Hypersensitivity reaction Fulminant hepatic failure Internal medicine Immunopathology Immunology medicine Eosinophilia medicine.symptom Young adult Liver function tests business medicine.drug |
| Zdroj: | International Journal of Clinical Practice. 59:988-991 |
| ISSN: | 1368-5031 |
| DOI: | 10.1111/j.1368-5031.2005.00550.x |
| Popis: | Carbamazepine is a widely used drug. It is commonly associated with hepatic abnormalities, ranging from an asymptomatic rise in liver function tests to acute liver failure. The most severe reaction occurs as part of a generalised hypersensitivity reaction, also known as drug reaction, eosinophilia and systemic symptoms (DRESS). We describe a case of a young adult who presented with non-specific symptoms, which progressed to fulminant hepatic failure, displaying the hallmarks of DRESS. We highlight the need for awareness of such an association. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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