Transition‐Metal‐Mediated or ‐Catalyzed Syntheses of Steroids and Steroid‐Like Compounds

Autor:	Barbara Eignerová, Filip Hessler, Martin Kotora
Rok vydání:	2011
Předmět:	Transition metal Chemistry medicine.medical_treatment Organic Chemistry Salt metathesis reaction medicine Enantioselective synthesis Organic chemistry Physical and Theoretical Chemistry Multiple bonds Combinatorial chemistry Catalysis Steroid
Zdroj:	European Journal of Organic Chemistry. 2012:29-42
ISSN:	1099-0690 1434-193X
DOI:	10.1002/ejoc.201100921
Popis:	This short review aims to summarize recent advances in the use of transition-metal-catalyzed and -mediated methodology for the synthesis of steroid and steroid-like skeletons reported in the last decade. The methodologies used include transition-metal-catalyzed or -mediated [2+2+2] and other cycloadditions, the Pauson–Khand reaction, cross-coupling and Heck reactions, processes based on the activation of single and multiple bonds, metathesis reactions, hydrovinylation, and other reactions. Several examples of total synthesesof steroid compounds [e.g., (+)- and (–)-estrone, desogestrel] by these procedures are presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::409eaf87fc449b073436a7c6d1465023 https://doi.org/10.1002/ejoc.201100921 Zobrazit plný text záznamu Plný text