Presence of spur cells as a highly predictive factor of mortality in patients with cirrhosis

Autor:	Alexandra Alexopoulou, Theoni Kanellopoulou, Sophia Pouriki, Larisa Vasilieva, Spyridon P. Dourakis, Aspasia Soultati
Rok vydání:	2014
Předmět:	Hemolytic anemia medicine.medical_specialty Cirrhosis Hepatology business.industry Anemia Gastroenterology medicine.disease Surgery Sepsis Log-rank test Liver disease Hepatocellular carcinoma Internal medicine medicine Risk factor business
Zdroj:	Journal of Gastroenterology and Hepatology. 29:830-834
ISSN:	0815-9319
DOI:	10.1111/jgh.12473
Popis:	Background and Aim The presence of spur-cell anemia (SCA) is due to lipid disturbances of the erythrocyte membrane and may develop in patients with advanced liver cirrhosis. The accurate predicting value of SC for survival has not been clarified. The aim of this study was to evaluate SCA as a prognostic indicator in patients with cirrhosis. Methods We prospectively evaluated clinical, laboratory parameters, and survival in patients with cirrhosis, with or without SCA, during the period 2008–2011. Patients who had at admission renal failure, other causes of hemolytic anemia, hepatocellular carcinoma, sepsis, and/or active bleeding, were excluded. One hundred sixteen patients with cirrhosis were included. The presence of SCA (SC rate higher or equal to 5% [≥ 5%]) was diagnosed in 36 (31%) patients. Results Patients with SCA compared to those without had more advanced liver disease (higher Model for End-Stage Liver Disease [MELD], P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4090e9c874c47eeea0f064ae8ba9287a https://doi.org/10.1111/jgh.12473 Zobrazit plný text záznamu Plný text