A novel bioassay based gold nanoribbon biosensor to aid the preclinical evaluation of anticancer properties
| Autor: | Seetharamaiah Nalini, M. B. Madhusudana Reddy, Sangaraju Shanmugam, Seetharamaiah Nandini, Jose Savio Melo, S. E. Neelagund, Gurukar Shivappa Suresh, Hunasepalya Nagaiah NaveenKumar |
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| Rok vydání: | 2016 |
| Předmět: |
Biocompatibility
Chemistry General Chemical Engineering Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Electrochemistry 01 natural sciences 0104 chemical sciences Electrochemical gas sensor Nanomaterials Ultraviolet visible spectroscopy Colloidal gold Bioassay 0210 nano-technology Biosensor |
| Zdroj: | RSC Advances. 6:60693-60703 |
| ISSN: | 2046-2069 |
| Popis: | In this work, we report a microbial biosensor fabricated for the preclinical assay of anticancer compounds. Gold nanoribbons were used as a transducer for mounting the microbe. For the synthesis of these unique Au nanostructures, quercetin stabilized gold nanoparticles (Q-AuNPs) were synthesized as a first step using onion peel. Later, dityrosine peptide was used as a sacrificial template for the synthesis of the gold nanoribbons (AuNRs). The structural morphology of the as-synthesized Au nanomaterial was examined using UV spectroscopy, XRD, SEM and TEM. The AuNRs were found to be |
| Databáze: | OpenAIRE |
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