Non-immune hydrops fetalis induced by parvovirus B19 – diagnosis during pregnancy and its perinatal consequences
| Autor: | N. P. Bondarenko, P. W. Lakatoch, W. P. Lakatoch |
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| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Neonatology, surgery and perinatal medicine. 8:59-64 |
| ISSN: | 2413-4260 2226-1230 |
| DOI: | 10.24061/2413-4260.viii.1.27.2018.10 |
| Popis: | Introduction: Asymptomatic flow of parvovirus infection during pregnancy in 25 -68% of cases which significantly delay the onset of specific diagnosis and complicates the earlier detection of signs of infection of the fetus, which subsequently leads to the development of severe and irreversible consequences. The purpose of the study: to study the diagnosis of non-immune fetal hydrop in maternal parvovirus infection and its perinatal consequences. The materials and methods: The report presents observations on 13 clinical cases of non-immune hydrop fetalis due to infection with parvovirus B19 confirmed by methods of specific diagnosis, traced effects for the fetus and further for the newborn. Study results: Ultrasound diagnosis of non-immune hydrop fetalis occurred during 12 weeks after the primary infection with parvovirus B19 during pregnancy, on average, the fetal hydrop was observed after 6 weeks from symptomatic manifestations of maternal infection. Independent reduction of non-immune hydrops occurred in 23% of cases. In 46% of cases, non-immune hydrops resulted from parvovirus B19 ending with fetal / newborn death. In 31% of cases, there were positive effects of intrauterine fetal treatment, timely delivery and symptomatic therapy of the newborn. Summary: It is proved that the most severe effects on the fetus are due to its infection in the 2 trimester of pregnancy, the most favorable course of infection with possible reduction of watery symptoms is observed at infection in third trimester of pregnancy. |
| Databáze: | OpenAIRE |
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