PREVALENCE RATE AND IMPACT OF ADDICTIVE DISORDERS ON THE COURSE OF HIV-INFECTION IN IN-PATIENTS

Autor: Andrey G. Diachkov, L. R Gorodnicheva, A. A. Yakovlev, V. B. Musatov, E. V. Strelyanaya, E. V Mikitenko
Rok vydání: 2017
Předmět:
Zdroj: Epidemiology and Infectious Diseases. 22:281-288
ISSN: 2411-3026
1560-9529
Popis: Aim of the study. To make an analysis of the prevalence rate and the impact of addictive disorders on the course of HIV-infection and evaluate the efficacy of the antiretroviral therapy. Methods and Materials. The retrospective analysis of medical records of HIV-positive patients, examined by the narcologist in the S.P. Botkin Clinical Infectious Diseases Hospital during the period of from September to November in 2014 and 2016. Results. Half of the patients (576 out of 1164 patients, 49.5%) treated in HIV-infection hospital required consultation of narcologist. In 2014 and 2016 men were more prevalent among such patients (73% and 76% accordingly), with a trend toward the involvement of older patients. Most prevalent narcological pathology among HIV-positive patients was opioid dependence (48% and 45% accordingly). Despite an increase of absolute numbers of narcologist’s consultations in 2016 the only group in which the relative gain from 17% to 26% was observed there was a group of patients suffered both opioid dependency and chronic alcoholism simultaneously. According to our data odds ratio for starting antiretroviral therapy in the hospital were higher in women and in patients with remission of chronic alcoholism. Percentage of patients who started antiretroviral therapy was insufficient - 30% among patients discharged after the complete in-hospital stay. Conclusion. The pattern of HIV epidemic among patients with addictive disorders does not differ from the general HIV-positive population. The gain in percentage of patients with comorbidity such as opioid dependency with alcohol abuse was observed. Patients manifested the alcohol abuse at the time of admission have lower chances to begin to receive ARVT comparing to those who were in remission.
Databáze: OpenAIRE
Externí odkaz: