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The liver is a highly complex organ involved in maintaining the health and balance of multiple systems of the body. It is found in the right upper quadrant of the abdomen and receives a dual blood supply from the portal vein and the hepatic artery. As such, vast amounts of nutrients enter the liver, providing the necessary materials and energy for carbohydrate, protein, and lipid synthesis and metabolism. The liver is also a vital site for the metabolism and clearance of exogenous drugs. In addition, the liver is a storage organ and plays a role in regulating the haematological and endocrine systems. This chapter discusses the liver’s macroscopic and microscopic anatomy from a functional perspective, followed by a thorough discussion of its various physiological functions. |
