ChemInform Abstract: A New Expedient Route to 2,6-Diaryl-3-cyano-4-(trifluoromethyl)pyridines

Autor:	I. Katsuyama, Katsuyoshi Shibata, Kazumasa Funabiki, Y. Yamaguchi, Masaki Matsui
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Trifluoromethyl Chemistry Aryl Potassium Organic chemistry chemistry.chemical_element General Medicine Acetonitrile
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199902143
Popis:	1-Aryl-4,4,4-trifluoro-1,3-butanediones 1 react with β-amino-β-arylacrylonitrile 2, readily available from acetonitrile with aryl nitriles in the presence of potassium t-butoxide, to afford the corresponding 2,6-diaryl-3-cyano-4-(trifluoromethyl)pyridines 3 in moderate to excellent yields.
Databáze:	OpenAIRE
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