An observational study to determine the status of serum and RBC folate in drug resistant epileptic children at a tertiary care centre in Western Rajasthan, India

Autor:	Bhawna Chaudhary, Ashish Gupta, Bindu Deopa
Rok vydání:	2020
Předmět:	medicine.medical_specialty business.industry Internal medicine medicine Observational study Drug resistance RBC Folate business Tertiary care
Zdroj:	International Journal of Contemporary Pediatrics. 7:1554
ISSN:	2349-3291 2349-3283
Popis:	Background: Drug resistant epilepsies constitute about 10-20% of childhood epilepsies and treated with higher doses and multiple AEDs. AEDs increases folate metabolism by enzyme induction thus causes deficiency of folic acid.Objective was to evaluate the effect on serum and RBC folate in children having drug resistant epilepsy.Methods: In a prospective observational study 83 drug resistant epileptic children of age 6months to 180 months fulfilled the inclusion criteria enrolled in study, from Oct 2014 to Nov 2016 for a period of two years. Serum and RBC folate levels were done in these children. Epileptic children already receiving folic acid supplementation/treatment were excluded from the study. Children with serum folate level
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::404690020b93cc6243ae451e8aa5fffd https://doi.org/10.18203/2349-3291.ijcp20202615 Zobrazit plný text záznamu