Patterns of Cerebrospinal Fluid Biomarkers and Amyloid Positron Emission Tomography in a Patient with Cerebral Amyloid Angiopathy-Related Inflammation

Autor:	Jae-Hong Lee, Hee Jae Jung, Yong Seo Koo, Yun Jik Park, Sungyang Jo, Ji-Yon Kim
Rok vydání:	2021
Předmět:	Pathology medicine.medical_specialty Amyloid medicine.diagnostic_test business.industry Inflammation medicine.disease Cerebrospinal fluid Positron emission tomography mental disorders medicine Cerebral amyloid angiopathy medicine.symptom business
Zdroj:	Journal of the Korean Neurological Association. 39:172-176
ISSN:	2288-985X 1225-7044
Popis:	Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a distinct subset of cerebral amyloid angiopathy characterized by the auto-inflammatory response to amyloid-laden small arteries of cerebral cortex and leptomeninges. Clinical features include cognitive-behavioral change, headache, focal neurologic deficits and seizure. Because anti-inflammatory treatments can rapidly relieve neurologic symptoms, early diagnosis is critical. Herein, we report a CAA-RI case with distinct laboratory findings of a decreased cerebrospinal fluid amyloid beta 1-42 level and relatively reduced florbetaben uptake in the focal inflammatory lesion during the acute phase of CAA-RI.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::40443f5729979cf45dc3fed8a7363149 https://doi.org/10.17340/jkna.2021.3.9 Zobrazit plný text záznamu