Patterns of Cerebrospinal Fluid Biomarkers and Amyloid Positron Emission Tomography in a Patient with Cerebral Amyloid Angiopathy-Related Inflammation
Autor: | Jae-Hong Lee, Hee Jae Jung, Yong Seo Koo, Yun Jik Park, Sungyang Jo, Ji-Yon Kim |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Journal of the Korean Neurological Association. 39:172-176 |
ISSN: | 2288-985X 1225-7044 |
Popis: | Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a distinct subset of cerebral amyloid angiopathy characterized by the auto-inflammatory response to amyloid-laden small arteries of cerebral cortex and leptomeninges. Clinical features include cognitive-behavioral change, headache, focal neurologic deficits and seizure. Because anti-inflammatory treatments can rapidly relieve neurologic symptoms, early diagnosis is critical. Herein, we report a CAA-RI case with distinct laboratory findings of a decreased cerebrospinal fluid amyloid beta 1-42 level and relatively reduced florbetaben uptake in the focal inflammatory lesion during the acute phase of CAA-RI. |
Databáze: | OpenAIRE |
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