Comparative biological properties of HA plasma-sprayed coatings having different crystallinities
| Autor: | Patrick Frayssinet, F. Tourenne, C. Delga, N. Rouquet, P. Conte, G. Bonel |
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| Rok vydání: | 1994 |
| Předmět: |
chemistry.chemical_classification
Materials science Biomedical Engineering Biophysics Mineralogy Bioengineering Surface finish Polymer engineering.material eye diseases Biomaterials Coating chemistry Chemical engineering Plasma sprayed Mammalian cell Phase (matter) Biological property engineering Alkaline phosphatase sense organs |
| Zdroj: | Journal of Materials Science: Materials in Medicine. 5:11-17 |
| ISSN: | 1573-4838 0957-4530 |
| DOI: | 10.1007/bf00121147 |
| Popis: | Plasma-sprayed HA-coatings used for orthopaedic surgery can contain different percentages of crystalline phase. The influence of the amount of crystalline and amorphous phase on the biological properties of coatings is not known. The aim of this study is to determine the effect of this coating characteristic on mammalian cell functions in vitro. It appears that 100% crystalline coatings have an inhibiting effect on cell proliferation and on alkaline phosphatase activity. A direct contact of the cells with the material is necessary to obtain this effect. The material evolves during the period of culture. Poorly crystalline coatings dissolve during the period of culture and the roughness parameters change during the same period. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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