Isolation of a precipitating antigen associated with bovine leukosis

Autor: O. R. Kaaden, M. Mussgay, F. Weiland, B. Dietzschold, O. C. Straub, B. Frenzel
Rok vydání: 1976
Předmět:
Zdroj: Veterinary Microbiology. 1:121-128
ISSN: 0378-1135
Popis: A precipitating antigen was isolated from bovine leukosis C-type particles. It was purified by ultracentrifugation, isoelectric focusing and sedimentation in sucrose gradients. The antigen — identified as a basic protein with a single polypeptide in the molecular weight range from 12 800 to 15 500 d — cross-reacted with antisera from bovine as well as ovine leukosis. A second antigen has been found in cytoplasmic extracts of cultivated lymphocytes and in NP40-treated bovine C-type particles.
Databáze: OpenAIRE