Autor:	M E Bos, G. Tetrault, Fred Christopher Zusi, G Whiting, Carroll Fi, Lewin Ah, P. Bouquin, Xina Nair
Rok vydání:	1994
Předmět:	Pharmacology Organic Chemistry Pharmacology toxicology Retinol Retinoic acid Pharmaceutical Science Biological activity Biology chemistry.chemical_compound Systemic toxicity chemistry Biochemistry Toxicity Molecular Medicine Pharmacology (medical) Biotechnology
Zdroj:	Pharmaceutical Research. 11:192-200
ISSN:	0724-8741
DOI:	10.1023/a:1018938920796
Popis:	Evaluation of 13-cis-12-substituted analogues of retinoic acid in a series of dermatologic screens has revealed that structural modifications can lead to selectivity and specificity. An analogue, 11-cis,13-cis-12-hydroxymethylretinoic acid, δ-lactone, has been found to have good activity and to be devoid of topical and systemic toxicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::40110ee79b01bd97c79f41da7d4d2299 https://doi.org/10.1023/a:1018938920796 Zobrazit plný text záznamu Full text from SpringerLink