Unsuspected carcinoma of the prostate in suprapubic prostatectomy specimens

Autor: Malcolm H. McGavran, Walter C. Bauer, M. Richard Carlin
Rok vydání: 1985
Předmět:
Zdroj: Urology. 26:607-615
ISSN: 0090-4295
DOI: 10.1016/0090-4295(85)90378-4
Popis: Fifty-five cases of unsuspected carcinoma were found in 847 consecutive suprapubic prostatectomy specimens. All 55 patients have been followed for a minimum of 5 years. The crude 5-year survival rate is 54 per cent. Twenty-four of these patients were followed for 10 years, and their survival rate is 37 per cent. The differentiation and size of the cancer have a direct bearing upon the clinical outcome. The 5- and 10-year survival rates for patients with well differentiated cancers are 75 per cent and 47 per cent, respectively. The 5- and 10-year survival rates for those with less than well differentiated cancers are 33 per cent and 14 per cent, respectively. We have presented evidence that patients with small, well differentiated cancers discovered by suprapubic prostatectomy need not have secondary radical prostatectomy: We have no evidence that conservative therapy, i.e., estrogens or castration, alters the prognosis in this group. The indications are that secondary radical prostatectomy may be a rational approach for treating the moderately or poorly differentiated cancers and the large cancers discovered by suprapubic prostatectomy.
Databáze: OpenAIRE