Spontaneous Epidural Hematomas due to Cerebral Venous Thrombosis in a Patient with Immune Thrombocytopenic Purpura
| Autor: | Dimitrios Ntantos, Angeliki Prevezianou, Petros Angelopoulos, Sevasti Bostantjopoulou, Eleni Karantali |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Romiplostim business.industry Dura mater Rehabilitation Blood stasis medicine.disease Thrombocytopenic purpura Thrombosis Surgery 03 medical and health sciences Venous thrombosis 0302 clinical medicine medicine.anatomical_structure Epidural hematoma Jugular vein medicine Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases. 29:105244 |
| ISSN: | 1052-3057 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2020.105244 |
| Popis: | Introduction Intracerebral haemorrhage in patients suffering from cerebral venous thrombosis (CVT) is relatively uncommon. CVT typically occurs in hypercoagulable state of various causes. Some drugs play a causative role in CVT and thrombopoietin receptor agonists are among them. Case summary We present a female patient with refractory immune thrombocytopenic purpura (ITP) treated with romiplostim, suffering from severe thrombosis of jugular vein expanding intracranially. Despite being treated with adequate anticoagulation, she developed spontaneous bilateral epidural and subdural hematomas with devastating outcome. Discussion To our knowledge, this is the first reported case of spontaneous atraumatic epidural hematomas due to CVT in adult patient. We support that in our patient, blood stasis leading to the dissection of dura mater, platelet dysfunction, and anticoagulation treatment contributed to the formation of the intracranial, extracerebral haemorrhages. |
| Databáze: | OpenAIRE |
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