A Smartphone-Interfaced, Flexible Electrochemical Biosensor Based on Graphene Ink for Selective Detection of Dopamine
| Autor: | Derrick Butler, Ritvik Muralidharan, Aida Ebrahimi, Vinay Chandrashekhar |
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| Rok vydání: | 2020 |
| Předmět: |
Detection limit
Materials science business.industry Graphene 010401 analytical chemistry Ascorbic acid 01 natural sciences Potentiostat 0104 chemical sciences law.invention X-ray photoelectron spectroscopy law Electrode Optoelectronics Electrical and Electronic Engineering Cyclic voltammetry business Instrumentation Biosensor |
| Zdroj: | IEEE Sensors Journal. 20:13204-13211 |
| ISSN: | 2379-9153 1530-437X |
| DOI: | 10.1109/jsen.2020.3005171 |
| Popis: | This study reports the fabrication of flexible electrochemical dopamine sensors using a facile, low temperature (300°C) process based on spin-coating of commercially available graphene ink onto a polyimide (PI) substrate. The electrochemical testing and surface characterization were achieved using cyclic voltammetry (CV), X-ray photoelectron spectroscopy (XPS), and atomic force microscopy (AFM). The graphene-ink based biosensor demonstrated a limit of detection (LoD) of 100 nM of dopamine in PBS and a dynamic concentration range up to 1 mM, with excellent specificity against uric acid and ascorbic acid. The sensor is also resilient against mechanical deformation ( $1~\mu \text{m}$ to 5 nM in artificial sweat. Wireless data transfer via Wi-Fi in tandem with an on-chip sensor integrated with an in-house built potentiostat is also developed to demonstrate the applicability of the platform for point-of-care applications. |
| Databáze: | OpenAIRE |
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