Hairy cell leukemia is infrequent in México and has a geographic distribution

Autor: Jorge Cortés-Franco, José Rodriguez‐Carrillo, Fernando Romero-García, David Gómez-Almaguer, Guillermo J. Ruiz-Argüelles, Leopolodo Mercado-Díaz, J Pizzuto, Enrique Torre-López, Olga G. Cantú-Rodríguez, Renán A. Góngora-Biachi, M. Guadalupe Apreza-Molina
Rok vydání: 1996
Předmět:
Zdroj: American Journal of Hematology. 52:316-318
ISSN: 1096-8652
0361-8609
DOI: 10.1002/(sici)1096-8652(199608)52:4<316::aid-ajh13>3.0.co;2-b
Popis: Considering that the prevalence of some hematologic malignancies may have a geographic distribution that could be related with its etiology, a group of 2,387 patients with acute leukemia (1,968 adults and 419 children) was studied along a 5-year period in six different locations within Mexico. Twenty-seven patients (16 males and 11 females) with hairy cell leukemia (HCL) were identified. The adjusted overall porportion of HCL, after excluding data from centers reporting only adults, was 1.12% of all leukemia cases; this figure is lower than that reported in the United States or England. The proportion of adult leukemic patients with HCL was significantly higher in the northern region of the country—where there are more people devoted to farming and agricultural activities—as compared with the central or southeastern regions (3.07 vs. 1.03% vs 0%; P < 0.05); possible explanations for these differences are briefly discussed. © 1996 Wiley-Liss, Inc.
Databáze: OpenAIRE
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