Malignant melanoma with osteosarcomatous differentiation in a lymph node metastasis

Autor:	Rajiv M. Patel, Paul W. Harms, Jasmine Saleh, Douglas R. Fullen, Michael L. Wang
Rok vydání:	2018
Předmět:	Pathology medicine.medical_specialty Histology business.industry Melanoma Dermatology Lymph node metastasis Primary lesion medicine.disease Pathology and Forensic Medicine Metastasis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis medicine Immunohistochemistry Medical history business Lymph node Histological examination
Zdroj:	Journal of Cutaneous Pathology. 45:701-704
ISSN:	0303-6987
Popis:	Osteocartilaginous differentiation in malignant melanoma is rare and can pose a diagnostic challenge. In previously reported cases, melanomas were predominantly located on acral and mucosal sites, with osteocartilaginous differentiation present in either primary or recurrent lesions. We report a case of a 52-year-old female with malignant melanoma located on the right upper back exhibiting osteosarcomatous differentiation only in the axillary lymph node metastasis. This case serves to highlight that the divergent differentiation can occur in lymph node metastases while being absent in the primary lesion. The patient's medical history, careful histological examination, and immunohistochemistry may be necessary for establishing the correct diagnosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3fe6986ab5be1782fe696a9876652a64 https://doi.org/10.1111/cup.13283 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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