A new transformation of aminopyridines upon diazotization in acetonitrile with the formation of N-pyridinylacetamides

Autor:	A. A. Chudinov, R. S. Dovbnya, Elena A. Krasnokutskaya, I. L. Filimonova, V. D. Ogorodnikov
Rok vydání:	2016
Předmět:	chemistry.chemical_compound Transformation (genetics) chemistry 010405 organic chemistry Organic chemistry General Chemistry 010402 general chemistry Hydrogen peroxide Acetonitrile Photochemistry 01 natural sciences 0104 chemical sciences Aminopyridines
Zdroj:	Russian Chemical Bulletin. 65:2312-2314
ISSN:	1573-9171 1066-5285
DOI:	10.1007/s11172-016-1583-9
Popis:	Diazotization of aminopyridines upon treatment with NaNO2 and H3PO4 in acetonitrile led to the formation of N-pyridinylacetamides. This reaction constitutes a convenient and general preparative method for the synthesis of 2-, 3-, and 4-N-pyridinylacetamides under mild conditions in good yields. The in situ oxidation of the thus obtained N-pyridinylacetamides with hydrogen peroxide gave good yields of pyridinylacetamide N-oxides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3fd806196b9bf9b5eb7cfd86d5095ef0 https://doi.org/10.1007/s11172-016-1583-9 Zobrazit plný text záznamu Full text from SpringerLink