| Popis: |
Department of Chemistry, University of Jodhpur, Jodhpur-142 001 Manuscript received 29 September 1984, revised 24 June 1985, accepted 11 September 1985 Isobutyl methyl ketone reacted with iodine in presence of heterocyclic tertiary bases, viz. pyridine, quinoline, isoquinoline, and ��-, ��- and \(\gamma\)-picolines using isopropanol as solvent, resulting in the formation of a series of quaternary N-(2-oxopentyl-4-methyl)ammonium iodides. When acetic acid was used as medium of reaction the triiodides of quaternary N-(2-oxopentyl-4-methyl)animonium iodides were isolated. On using excess of heterocyclic tertiary base in the reaction, no triiodide formation took place. The quaternary compounds responded to the characteristic enol betaine test. These compounds showed antibacterial activity at 100 ppm against human pathogen, Staphylococcus aureus. |
