Follicular adenoma associated with spindle cell proliferation, papillary adenoma and colloid goitre in a dromedary camel
| Autor: | Hassan Abu Damir, Adam M. Adam, Mohamed H. Tageldin, Mahmoud A. Ali, Elhag A. Omer |
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| Rok vydání: | 2015 |
| Předmět: |
endocrine system
Pathology medicine.medical_specialty endocrine system diseases Follicular Cyst Adenoma 040301 veterinary sciences Thyroid Thyroid adenoma Papillary Adenoma 04 agricultural and veterinary sciences Biology medicine.disease Malignancy Pathology and Forensic Medicine 0403 veterinary science 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis medicine Carcinoma Anatomy Hyaline |
| Zdroj: | Comparative Clinical Pathology. 25:241-245 |
| ISSN: | 1618-565X 1618-5641 |
| DOI: | 10.1007/s00580-015-2183-z |
| Popis: | In humans, spindle cell lesions associated with thyroid adenoma or carcinoma are rare. A cross section of the thyroid of a dromedary camel showed follicular cysts, and microscopically, both thyroid lobes showed colloid goitre. The left lobe showed spindle cell proliferation associated with follicular adenoma without evidence of capsular or vascular invasion. The spindle cell lesion had cells featuring ground glass or pseudoinclusion nuclei and showed extensive haemorrhage, hyalinization and thrombosis. The right thyroid lobe showed papillary adenoma. Immunohistochemistry showed negative expression for malignancy. Serum Se, free tri-iodothyronine (fT3) and free thyroxine (fT4) values were low and CK activity was high. The histological features were unusual and merit reporting. |
| Databáze: | OpenAIRE |
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