Evaluation of bronchoscopic lung volume reduction coil treatment results in patients with severe emphysema
| Autor: | Hatice Yilmaz, Askin Gülsen, Pelin Girgin, Fidan Sever, Necdet Batuhan Tamci |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty COPD Lung business.industry Exhalation medicine.disease Pulmonary function testing Surgery 03 medical and health sciences Pneumonia 0302 clinical medicine medicine.anatomical_structure 030228 respiratory system Pneumothorax medicine.artery Pulmonary artery Immunology and Allergy Medicine Arterial blood 030212 general & internal medicine business Genetics (clinical) |
| Zdroj: | The Clinical Respiratory Journal. 11:585-592 |
| ISSN: | 1752-6981 |
| DOI: | 10.1111/crj.12387 |
| Popis: | Introduction Bronchoscopic lung volume reduction coil (BLVR-C) implantation is an alternative therapeutic approach that can be applied together with medical treatment for patients with severe emphysema. BLVR-C is both easier and safer in terms of complications than volume reduction surgery. This study aimed to evaluate medium-term outcomes following BLVR-C treatment. Methods Forty patients who underwent BLVR-C between September 2013 and March 2014 were reviewed retrospectively. We compared changes between the baseline and 6-month post-procedural results with respect to pulmonary function tests, a 6-min walk test (6MWT), chronic obstructive pulmonary disease (COPD) assessment test (CAT), St. George's Respiratory Questionnaire (SGRQ), and pulmonary artery pressure (PAP) and arterial blood gas analyses. Secondary outcomes included procedure-related and follow-up complications. Results An average of 9.5 (range: 5–11) coils were placed per lung in an average procedural duration of 20.8 ± 7.0 min (range: 9–45) min. Six months after BLVR-C treatment, significant improvements were observed in patients’ pulmonary function tests and quality of life. Changes were observed in the forced exhalation volume in 1 s (+150 mL), residual volume (−14.5%), 6MWT (+48 m), SGRQ (−10.5) and CAT Score (−7.5). Changes in the PAP and partial pressure of carbon dioxide values were not significant, and pneumothorax did not occur. In a 6-month follow-up, 11 cases of COPD exacerbation (41.4%), 7 cases of pneumonia (16.9%) and 1 death (2%) occurred. Treatment in 1 case was postponed because of hypotension and bradycardia during the process. Conclusion BLVR-C treatment appears to be effective over the medium-term and safe for patients with severe emphysema. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|