Design, synthesis and cleaving activity of an abiotic nuclease based on a manganese(III) porphyrin complex bearing two acridine moieties
| Autor: | Cathy Drexler, Mir Wais Hosseini, Geneviève Pratviel, Bernard Meunier |
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| Rok vydání: | 1998 |
| Předmět: |
Abiotic component
Nuclease biology Metals and Alloys chemistry.chemical_element General Chemistry Manganese Photochemistry Porphyrin Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound chemistry Design synthesis Cleave Polymer chemistry Acridine polycyclic compounds Materials Chemistry Ceramics and Composites biology.protein DNA |
| Zdroj: | Chemical Communications. :1343-1344 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/a801095a |
| Popis: | The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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