Investigating the Role of Coil Designs and Anatomical Variations in Cerebellar TMS
Autor: | Yifei Wang, David Jiles, Erik Lee, Xiaojing Zhong, Priyam Rastogi |
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Rok vydání: | 2019 |
Předmět: |
010302 applied physics
Cerebellum medicine.diagnostic_test Computer science Cognitive domain medicine.medical_treatment Cerebellar function Magnetic resonance imaging 01 natural sciences Neuromodulation (medicine) Electronic Optical and Magnetic Materials Transcranial magnetic stimulation medicine.anatomical_structure nervous system Electromagnetic coil 0103 physical sciences medicine Electrical and Electronic Engineering Neuroscience Neurostimulation |
Zdroj: | IEEE Transactions on Magnetics. 55:1-5 |
ISSN: | 1941-0069 0018-9464 |
DOI: | 10.1109/tmag.2018.2890069 |
Popis: | Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique that is used for treating various neurological disorders such as major depressive disorder. TMS has been gaining popularity in the field of neurostimulation of the cerebellum, since the cerebellum is a complex structure connected with almost the entire central nervous system and TMS has promise for non-invasively probing cerebellar function. Recent studies have discovered that the cerebellum plays an important role not only in motor planning and behavior but also in the cognitive domain. However, few studies have explored how different coil designs and anatomical variations affect the effectiveness of cerebellar TMS. Therefore, in this paper, we investigated the effects of cerebellar TMS with different coil designs positioning on several locations. Finite-element modeling was conducted with Figure-8 coil and D-B80 coil. Each coil was positioned in the center, 1 and 3 cm to the left of center of the cerebellum, and all the locations were tangential to the scalp at a distance of 5 mm. Furthermore, 50 MRI derived head models were used in the computer modeling to examine how anatomical variations affect the distribution and intensity of electric field in cerebellar TMS. |
Databáze: | OpenAIRE |
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