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Background Validated disease activity scores and damage measurements were developed over time in order to allow a better way to evaluate patients and decide treatment plans.There are scores designed for a great variety of vasculitis like Birmingham Activity Score and others that are more specific like Behcet9s Disease Current Activity Form2006. Objectives To evaluate the ability of the activity scores (BVASv3and BDCAF)to predict damage,and the influence of immunosuppressive therapy on damage progression,as measured byVDI, in a group of patients with Behcet9s Disease. Methods A study was performed on a cohort of patients diagnosed with Behcet9s Disease under surveillance in one tertiary Rheumatology Centre, from a non-endemic area.All documented cases of Behcet9s Disease have been diagnosed according to The International Criteria for Behcet9s Disease.The Birmingham Activity Score (BVAS)v3, Behcet9s Disease Current Activity Form2006 (BDCAF)and Vasculitis Damage index (VDI) were calculated for all patients. Spearman9s correlation coefficients were calculated between BVASv3 Score, BDCAF, VDI and immunosuppressive treatment.WindowsExcel/SPSS20.0 has been used to analyse the data. Results 20 patients were included in the study, with ages at the time of the diagnosis between 13and 60years, 14 (70%) under the age of 40,with a male predominance 60% (12 patients). All patients presented active disease at the time of the diagnosis. In the clinical case series, Spearman9s rank correlation coefficient between BVASv3 and BDCAFwas strong r=0,862with p Conclusions Birmingham Vasculitis Activity score (BVAS) v3 and Behcet9s Disease Current Activity Form2006 (BDCAF) are reliable tools for evaluating disease activity in patients with Behcet9s Disease. They are able to anticipate the need for immunosuppressive therapy and the damage progression, as calculated with Vasculitis Damage Index (VDI). References Mukhtyar C, Lee R, et al. Modification and validation of the Birmingham vasculitis activity score, Ann Rheum Dis, 2009. Flossmann O, et al. Development of comprehensive disease assessment in systemic vasculitis. Ann Rheum Dis, 2007. Disclosure of Interest None declared |
